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Mode of action chloramphenicol inhibits bacterial protein synthesis by blocking the cialis kanada. peptidyl transferase step by binding to the 50s ribosomal subunit and preventing attachment of aminoacyl trna to the ribosome.

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chloramphenicol binds to the 50s ribosomal subunit and blocks fundamental ribosomal functions, such as peptidyltransferase ptase activity, binding and movement of ribosomal substrates through the ptase center and translation termination.

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